MOTS-c (Mitochondrial-Derived Peptide) – Lyophilized Vial

Price range: $36.00 through $175.00

MOTS-c is a 16-amino acid peptide encoded within the mitochondrial genome. Known as a “mitochondrial-derived peptide” (MDP), it has been shown to regulate metabolic functions by targeting the folate-methionine cycle and activating AMPK. Our MOTS-c is synthesized to >99% purity and lyophilized for stability. Strictly for in-vitro laboratory research and development use only; not for human consumption.

Description

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) represents a new class of peptides. Unlike most hormones which are encoded in the nuclear DNA, MOTS-c is encoded in the DNA of the mitochondria itself.

Mechanism of Action

  • AMPK Activation: Research suggests MOTS-c translocates to the nucleus in response to metabolic stress, where it regulates adaptive responses similar to those seen in exercise.

  • Glucose Regulation: Studies in mice have shown it to improve insulin sensitivity and prevent diet-induced obesity.

  • Metabolic Flexibility: It is often studied as an “exercise mimetic” for its ability to enhance cellular energy metabolism.

Quality Assurance

  • Sequence: Met-Arg-Trp-Qul-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg

  • Purity: >99% by HPLC

  • Form: Sterile White Lyophilized Powder

FOR RESEARCH USE ONLY:

This product is sold strictly as a chemical reference standard for in-vitro laboratory research purposes only. It is not intended for human or animal consumption, injection, or administration of any kind. This product is not intended to diagnose, treat, cure, or prevent any disease or medical condition. Bodily introduction into humans or animals is strictly prohibited. For use by qualified research professionals only.

Additional information

MG

5, 10, 20, 40

Research reference

A 16-amino-acid mitochondrial-derived peptide encoded in the mitochondrial 12S rRNA region. Studied in metabolic and mitochondrial-signalling research, including AMPK pathway models.

Class
Mitochondrial-derived peptide
CAS
1627580-64-6
Formula
C101H152N28O22S2
Storage
Lyophilized: -20°C. Reconstituted: 2-8°C.

Research use only. Sold as a chemical reference standard for in-vitro laboratory research. Not for human or veterinary use, and not a drug, food or cosmetic.