Kisspeptin-10 (Kp-10) – Lyophilized Peptide

Price range: $50.00 through $80.00

Kisspeptin-10 is a 10-amino acid peptide fragment derived from the KISS1 gene. It functions as the primary ligand for the G-protein coupled receptor GPR54 (Kiss1R). Research identifies it as the “gatekeeper” of puberty and reproduction, stimulating the secretion of Gonadotropin-Releasing Hormone (GnRH). Our lyophilized Kisspeptin-10 is HPLC-verified for >99% purity. Strictly for in-vitro laboratory research and development use only; not for human consumption.

Description

The Kisspeptin family of peptides plays a critical role in the regulation of the Hypothalamic-Pituitary-Gonadal (HPG) axis. Kisspeptin-10 is the shortest endogenous fragment that retains full receptor binding efficacy, making it a highly efficient tool for neuroendocrine research.

Mechanism of Action

  • GnRH Release: Upon binding to GPR54 in the hypothalamus, it triggers a robust release of GnRH.

  • Downstream Signaling: This cascade stimulates the pituitary gland to release Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH).

  • Pulsatile Nature: Research suggests it can reset or jumpstart the hormonal feedback loop without the suppression seen in exogenous hormone administration.

Quality Assurance

  • Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2

  • Purity: >99% Verified by HPLC

  • Form: Sterile White Lyophilized Powder

FOR RESEARCH USE ONLY:

This product is sold strictly as a chemical reference standard for in-vitro laboratory research purposes only. It is not intended for human or animal consumption, injection, or administration of any kind. This product is not intended to diagnose, treat, cure, or prevent any disease or medical condition. Bodily introduction into humans or animals is strictly prohibited. For use by qualified research professionals only.

Additional information

MG

5, 10

Research reference

The C-terminal decapeptide fragment of kisspeptin, an endogenous ligand of the KISS1R (GPR54) receptor. Used in reproductive-endocrinology research examining GnRH regulatory pathways.

Class
KISS1R decapeptide ligand
CAS
374675-21-5
Formula
C63H83N17O14
Storage
Lyophilized: -20°C. Reconstituted: 2-8°C.

Research use only. Sold as a chemical reference standard for in-vitro laboratory research. Not for human or veterinary use, and not a drug, food or cosmetic.